Anti-YTHDF2 Polyclonal Antibody

英文名称

Anti-YTHDF2 Polyclonal Antibody

别名

CLL associated antigen KW 14;HGRG8;NY REN 2;YTH domain family protein 2;YTH domain family;member 2;YTHDF2

宿主

Rabbit

稀释比例

WB 1:1000-3000.

Gene ID

51441

保存

Store at -20°C. Avoid freeze / thaw cycles.

Swiss Prot

Q9Y5A9

蛋白分子量

59/62kDa

储存液

Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

亚细胞定位

Nucleus Cytoplasm

免疫原

Recombinant protein of human YTHDF2

亚型

IgG

纯化方法

Affinity purification

背景资料

This gene encodes a member of the YTH (YT521-B homology) superfamily containing YTH domain. The YTH domain is typical for the eukaryotes and is particularly abundant in plants. The YTH domain is usually located in the middle of the protein sequence and may function in binding to RNA. In addition to a YTH domain, this protein has a proline rich region which may be involved in signal transduction. An Alu-rich domain has been identified in one of the introns of this gene, which is thought to be associated with human longevity. In addition, reciprocal translocations between this gene and the Runx1 (AML1) gene on chromosome 21 has been observed in patients with acute myeloid leukemia. This gene was initially mapped to chromosome 14, which was later turned out to be a pseudogene. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.

Public Immunogen Range

230-579aa

克隆类型

Polyclonal Antibody

交叉反应

Human

应用

WB

规格

50ul 100ul